Tissue stem cells and cancer stem cells: interplay between time, diet and epigenetics

· Oxford

Adult stem cells are a rare population of undifferentiated cells found throughout our bodies which are able to divide infinitely and give rise to the different types of cells that maintain the body’s tissues and organs. Salvador Aznar’s laboratory is interested in studying how these adult stem cells maintain tissue homeostasis and why they fail to function properly during ageing and tumorigenesis.

Prof Aznar will present their latest data regarding the impact our diet has on the timing of stem cell function and its profound effects on stem cells ageing. He will also discuss their recent findings on the influence that the fatty acid content of our diet has on metastatic-initiating cells, as well as recent work indicating that our diet exerts striking epigenetic effects on metastatic stem cells which can be therapeutically targeted.